Article
Differential splicing in the extracellular region of fibroblast growth factor receptor 1 generates receptor variants with different ligand-binding specificities.
Molecular and cellular biology - 1 Jan 1992
Werner S, Duan D S, de Vries C, Peters K G, Johnson D E, Williams L T
Abstract excerpt
We have cloned a genomic region of the murine fibroblast growth factor (FGF) receptor 1 (FGFR1) gene that includes three alternative exons for the third immunoglobulinlike domain in the extracellular region of the receptor. The mRNA of one of these splice variants encodes a secreted receptor that lacks transmembrane and cytoplasmic sequences as well as a portion of the third immunoglobulinlike domain. Highest...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
