Article
Fibroblast growth factor receptors: lessons from the genes.
Trends in biochemical sciences - 1 Feb 1998
Burke D, Wilkes D, Blundell T L, Malcolm S
Abstract excerpt
The fibroblast growth factor receptors (FGFRs) are a family of transmembrane tyrosine kinases involved in signalling via interactions with the family of fibroblast growth factors (FGFs). Genetic findings have provided a way of dissecting these interactions. Mutations in three members of the FGFR family have been found in patients with birth defects involving craniosynostosis (premature fusion of the cranial...
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