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Article

Whole genome and transcriptome analysis of a novel AML cell line with a normal karyotype.

Leukemia research - 1 Jul 2015

Gosse Géraldine, Celton Magalie, Lamontagne Vikie, Forest Audrey, Wilhelm Brian T

Abstract excerpt

Acute myeloid leukemia (AML) occurs when hematopoietic progenitor cells acquire genetic defects blocking the regulation of normal growth and differentiation. Although recurrent translocations have been identified in AML, almost half of adult AML patients present with a normal karyotype (NK-AML). While cell line models exist to study AML, they frequently have abnormal/unstable karyotypes, while primary cells from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25934047
DOI: 10.1016/j.leukres.2015.03.017

Genes

GATA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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