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Article

Systems biology analysis reveals NFAT5 as a novel biomarker and master regulator of inflammatory breast cancer.

Journal of translational medicine - 1 May 2015

Remo Andrea, Simeone Ines, Pancione Massimo, Parcesepe Pietro, Finetti Pascal, Cerulo Luigi, Bensmail Halima, Birnbaum Daniel, Van Laere Steven J, Colantuoni Vittorio, Bonetti Franco, Bertucci François, Manfrin Erminia, Ceccarelli Michele

Abstract excerpt

BACKGROUND: Inflammatory breast cancer (IBC) is the most rare and aggressive variant of breast cancer (BC); however, only a limited number of specific gene signatures with low generalization abilities are available and few reliable biomarkers are helpful to improve IBC classification into a molecularly distinct phenotype. We applied a network-based strategy to gain insight into master regulators (MRs) linked to...

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Source

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Identifiers

PMID: 25928084
DOI: 10.1186/s12967-015-0492-2
PMCID: PMC4438533

Genes

NFAT5
CTNNB1
MGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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