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Article

NF-kappa B genes have a major role in Inflammatory Breast Cancer

4 Feb 2008

Abstract excerpt

BACKGROUND: IBC (Inflammatory Breast cancer) is a rare form of breast cancer with a particular phenotype. New molecular targets are needed to improve the treatment of this rapidly fatal disease. Given the role of NF-kappaB-related genes in cell proliferation, invasiveness, angiogenesis and inflammation, we postulated that they might be deregulated in IBC. METHODS: We measured the mRNA expression levels of 60...

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PMID: 18248671
DOI: 10.1186/1471-2407-8-41

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