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Imputation of sequence level genotypes in the Franches-Montagnes horse breed.

Genetics, selection, evolution : GSE - 1 Oct 2014

Frischknecht Mirjam, Neuditschko Markus, Jagannathan Vidhya, Drögemüller Cord, Tetens Jens, Thaller Georg, Leeb Tosso, Rieder Stefan

Abstract excerpt

BACKGROUND: A cost-effective strategy to increase the density of available markers within a population is to sequence a small proportion of the population and impute whole-genome sequence data for the remaining population. Increased densities of typed markers are advantageous for genome-wide association studies (GWAS) and genomic predictions. METHODS: We obtained genotypes for 54 602 SNPs (single nucleotide...

Topics

Animals
Female
Genome-Wide Association Study
Genomics
Genotype
High-Throughput Nucleotide Sequencing
Horses
Male
Pedigree
Polymorphism, Single Nucleotide
Software

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Identifiers

PMID: 25927638
DOI: 10.1186/s12711-014-0063-7
PMCID: PMC4180851

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