Design of a low-density SNP chip for the main Australian sheep breeds and its effect on imputation and genomic prediction accuracy.

doi:10.1111/age.12340

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Article

Design of a low-density SNP chip for the main Australian sheep breeds and its effect on imputation and genomic prediction accuracy.

Animal genetics - 1 Oct 2015

Bolormaa S, Gore K, van der Werf J H J, Hayes B J, Daetwyler H D

Abstract excerpt

Genotyping sheep for genome-wide SNPs at lower density and imputing to a higher density would enable cost-effective implementation of genomic selection, provided imputation was accurate enough. Here, we describe the design of a low-density (12k) SNP chip and evaluate the accuracy of imputation from the 12k SNP genotypes to 50k SNP genotypes in the major Australian sheep breeds. In addition, the impact of...

Topics

Animals
Australia
Breeding
Gene Frequency
Genomics
Genotype
Meat
Oligonucleotide Array Sequence Analysis
Phenotype
Polymorphism, Single Nucleotide
Sheep, Domestic

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Open in PubMed

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PMID: 26360638
DOI: 10.1111/age.12340

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