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Article

BAG3-related myopathy, polyneuropathy and cardiomyopathy with long QT syndrome.

Journal of muscle research and cell motility - 1 Dec 2015

Kostera-Pruszczyk Anna, Suszek Małgorzata, Płoski Rafał, Franaszczyk Maria, Potulska-Chromik Anna, Pruszczyk Piotr, Sadurska Elżbieta, Karolczak Justyna, Kamińska Anna M, Rędowicz Maria Jolanta

Abstract excerpt

BAG3 belongs to BAG family of molecular chaperone regulators interacting with HSP70 and anti-apoptotic protein Bcl-2. It is ubiquitously expressed with strong expression in skeletal and cardiac muscle, and is involved in a panoply of cellular processes. Mutations in BAG3 and aberrations in its expression cause fulminant myopathies, presenting with progressive limb and axial muscle weakness, and respiratory...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26545904
DOI: 10.1007/s10974-015-9431-3
PMCID: PMC4762926

Genes

BAG3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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