Article
Lack of an association of PD-1 and its ligand genes with Behcet's disease in a Chinese Han population.
PloS one - 1 Jan 2011
Meng Qianli, Guo Haike, Hou Shengping, Jiang Zhengxuan, Kijlstra Aize, Yang Peizeng
Abstract excerpt
BACKGROUND: Behcet's disease is a chronic, multi-systemic autoimmune disease. Programmed cell death 1 (PD-1) gene is one of non-human leucocyte antigen genes. It has been demonstrated to be associated with several autoimmune diseases. However, only a few studies have addressed the association of ligand genes of PD-1, PD-L1 and PD-L2 with autoimmune disease. The purpose of this study was to analyze the potential...
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