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FOXA2 regulates a network of genes involved in critical functions of human intestinal epithelial cells

29 Apr 2015

Abstract excerpt

The forkhead box A (FOXA) family of pioneer transcription factors is critical for the development of many endoderm-derived tissues. Their importance in regulating biological processes in the lung and liver is extensively characterized, though much less is known about their role in intestine. Here we investigate the contribution of FOXA2 to coordinating intestinal epithelial cell function using postconfluent Caco2...

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PMID: 25921584
DOI: 10.1152/physiolgenomics.00024.2015

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