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Article

GATA4 Is Sufficient to Establish Jejunal Versus Ileal Identity in the Small Intestine

24 Jan 2017

Abstract excerpt

BACKGROUND & AIMS: Patterning of the small intestinal epithelium along its cephalocaudal axis establishes three functionally distinct regions: duodenum, jejunum, and ileum. Efficient nutrient assimilation and growth depend on the proper spatial patterning of specialized digestive and absorptive functions performed by duodenal, jejunal, and ileal enterocytes. When enterocyte function is disrupted by disease or...

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PMID: 28462382
DOI: 10.1016/j.jcmgh.2016.12.009

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