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Article

Genome-wide association data suggest ABCB1 and immune-related gene sets may be involved in adult antisocial behavior.

Translational psychiatry - 28 Apr 2015

Salvatore J E, Edwards A C, McClintick J N, Bigdeli T B, Adkins A, Aliev F, Edenberg H J, Foroud T, Hesselbrock V, Kramer J, Nurnberger J I, Schuckit M, Tischfield J A, Xuei X, Dick D M

Abstract excerpt

Adult antisocial behavior (AAB) is moderately heritable, relatively common and has adverse consequences for individuals and society. We examined the molecular genetic basis of AAB in 1379 participants from a case-control study in which the cases met criteria for alcohol dependence. We also examined whether genes of interest were expressed in human brain. AAB was measured using a count of the number of Antisocial...

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Identifiers

PMID: 25918995
DOI: 10.1038/tp.2015.36
PMCID: PMC4462601

Genes

ABCB1

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