Article
Genome-Wide Association Studies of a Broad Spectrum of Antisocial Behavior.
JAMA psychiatry - 1 Dec 2017
Tielbeek Jorim J, Johansson Ada, Polderman Tinca J C, Rautiainen Marja-Riitta, Jansen Philip, Taylor Michelle, Tong Xiaoran, Lu Qing, Burt Alexandra S, Tiemeier Henning, Viding Essi, Plomin Robert, Martin Nicholas G, Heath Andrew C, Madden Pamela A F, Montgomery Grant, Beaver Kevin M, Waldman Irwin, Gelernter Joel, Kranzler Henry R, Farrer Lindsay A, Perry John R B, Munafò Marcus, LoParo Devon, Paunio Tiina, Tiihonen Jari, Mous Sabine E, Pappa Irene, de Leeuw Christiaan, Watanabe Kyoko, Hammerschlag Anke R, Salvatore Jessica E, Aliev Fazil, Bigdeli Tim B, Dick Danielle, Faraone Stephen V, Popma Arne, Medland Sarah E, Posthuma Danielle
Abstract excerpt
Importance: Antisocial behavior (ASB) places a large burden on perpetrators, survivors, and society. Twin studies indicate that half of the variation in this trait is genetic. Specific causal genetic variants have, however, not been identified. Objectives: To estimate the single-nucleotide polymorphism-based heritability of ASB; to identify novel genetic risk variants, genes, or biological pathways; to test for...
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