Article

Peripheral blood cell-type and sex-specific signatures of alcohol misuse revealed by single-cell transcriptomics

2025-05-27

Abstract excerpt

<h4>ABSTRACT</h4> Alcohol use disorder (AUD) is a complex condition with diverse molecular underpinnings. Chronic alcohol exposure is associated with alterations in both innate and adaptive immune cell populations that in turn contribute to AUD susceptibility and severity, suggesting a bidirectional gene-environment relationship. Yet, most clinical AUD studies of this system have relied on indirect measurement of...

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Literature Corpus work: bc10c723-2916-5d18-9d6d-01e256661211
DOI: 10.1101/2025.05.21.655347

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