Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A ΩX a V motif in the Rift Valley fever virus NSs protein is essential for degrading p62, forming nuclear filaments and virulence

27 Apr 2015

Abstract excerpt

Rift Valley fever virus (RVFV) is a single-stranded RNA virus capable of inducing fatal hemorrhagic fever in humans. A key component of RVFV virulence is its ability to form nuclear filaments through interactions between the viral nonstructural protein NSs and the host general transcription factor TFIIH. Here, we identify an interaction between a ΩXaV motif in NSs and the p62 subunit of TFIIH. This motif in NSs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fire effects on ecosystems
Share to Viral Infections and Outbreaks Research
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25918396
DOI: 10.1073/pnas.1503688112

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A ΩX a V motif in the Rift Valley fever virus NSs protein is essential for degrading p62, forming nuclear filaments and virulencePMID 25918396Read ↗

Rift Valley fever virus NSs protein functions and the similarity to other bunyavirus NSs proteinsSemantic proximity Read ↗

Mechanistic Insight into the Host Transcription Inhibition Function of Rift Valley Fever Virus NSs and Its Importance in Virulence.Semantic proximity Read ↗

Rift Valley fever virus NSs inhibits host transcription independently of the degradation of dsRNA-dependent protein kinase PKR.Semantic proximity Read ↗

hnRNPA2B1 recognizes RNA virus SFTSV infection through mitochondrial DNASemantic proximity Read ↗

NSs Filament Formation Is Important but Not Sufficient for RVFV Virulence In VivoSemantic proximity Read ↗

Affinity tag free purification of SARS-Cov-2 N protein and its crystal structure in complex with ssDNASemantic proximity Read ↗

Induction of DNA Damage Signaling upon Rift Valley Fever Virus Infection Results in Cell Cycle Arrest and Increased Viral ReplicationSemantic proximity Read ↗

The NSs Protein Encoded by the Virulent Strain of Rift Valley Fever Virus Targets the Expression of Abl2 and the Actin Cytoskeleton of the Host, Affecting Cell Mobility, Cell Shape, and Cell-Cell Adhesion.Semantic proximity Read ↗

Human DDX17 Unwinds Rift Valley Fever Virus Non-Coding RNAsSemantic proximity Read ↗

Nucleoprotein filament formation is the structural basis for bacterial protein H-NS gene silencing.Semantic proximity Read ↗

Large-Scale Chromatin Immunoprecipitation with Promoter Sequence Microarray Analysis of the Interaction of the NSs Protein of Rift Valley Fever Virus with Regulatory DNA Regions of the Host GenomeSemantic proximity Read ↗

A SAP30 complex inhibits IFN-beta expression in Rift Valley fever virus infected cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.