Article
The NSs Protein Encoded by the Virulent Strain of Rift Valley Fever Virus Targets the Expression of Abl2 and the Actin Cytoskeleton of the Host, Affecting Cell Mobility, Cell Shape, and Cell-Cell Adhesion.
Journal of virology - 9 Dec 2020
Bamia Aline, Marcato Vasco, Boissière Magali, Mansuroglu Zeyni, Tamietti Carole, Romani Mattea, Simon Dominique, Tian Guanfang, Niedergang Florence, Panthier Jean-Jacques, Flamand Marie, Souès Sylvie, Bonnefoy Eliette
Abstract excerpt
Rift Valley fever virus (RVFV) is a highly pathogenic zoonotic arbovirus endemic in many African countries and the Arabian Peninsula. Animal infections cause high rates of mortality and abortion among sheep, goats, and cattle. In humans, an estimated 1 to 2% of RVFV infections result in severe disease (encephalitis, hepatitis, or retinitis) with a high rate of lethality when associated with hemorrhagic fever. The...
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