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Article

Targeting KIT in melanoma: a paradigm of molecular medicine and targeted therapeutics.

Biochemical pharmacology - 1 Sept 2010

Woodman Scott E, Davies Michael A

Abstract excerpt

Despite multiple clinical trials utilizing a spectrum of therapeutic modalities, melanoma remains a disease with dismal outcomes in patients with advanced disease. However, it is now clear that melanoma is not a single entity, but can be molecularly divided into subtypes that generally correspond to the anatomical location of the primary melanoma. Melanomas from acral lentiginous, mucosal, and chronic sun-damaged...

Topics

Antineoplastic Agents
Humans
Melanoma
Mutation
Proto-Oncogene Proteins c-kit
Skin Neoplasms

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 20457136
DOI: 10.1016/j.bcp.2010.04.032
PMCID: PMC3935736

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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