Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

C-kit-mutated melanomas: the Chinese experience.

Current opinion in oncology - 1 Mar 2013

Si Lu, Guo Jun

Abstract excerpt

PURPOSE OF REVIEW: Malignant melanoma is the most frequent cause of mortality in skin cancer. Unlike Caucasians, mucosal and acral melanomas account for approximately 65% of all melanomas in Chinese. Genetic mutations of c-kit are detected in mucosal and acral melanomas, which thus can be regarded as molecular targets for treatments. This review describes the recent proceedings in the c-kit-targeted molecular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Asian People
Share to Melanoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Molecular Targeted Therapy

Share to Protein Kinase Inhibitors

Share to Proto-Oncogene Mas

Share to Proto-Oncogene Proteins c-kit

Share to Skin Neoplasms

Source

Identifiers

PMID: 23299198
DOI: 10.1097/CCO.0b013e32835dafcc

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

C-kit-mutated melanomas: the Chinese experience.PMID 23299198Read ↗

KIT and Melanoma: Biological Insights and Clinical Implications.Semantic proximity Read ↗

Large-Scale Analysis of <i>KIT</i> Aberrations in Chinese Patients with MelanomaSemantic proximity Read ↗

c-KIT signaling as the driving oncogenic event in sub-groups of melanomas.Semantic proximity Read ↗

Mucosal melanomas of the head and neck: new aspects of the clinical outcome, molecular pathology, and treatment with c-kit inhibitors.Semantic proximity Read ↗

Imatinib in c-KIT-mutated metastatic solid tumors: A multicenter trial of Korean Cancer Study Group (UN18-05 Trial).Semantic proximity Read ↗

C-kit expression of melanocytic neoplasm and association with clinicopathological parameters and anatomic locations in Chinese people.Semantic proximity Read ↗

BRAF, C-KIT, and NRAS mutations correlated with different clinicopathological features: an analysis of 691 melanoma patients from a single centerSemantic proximity Read ↗

Analysis of KIT mutations and c-KIT expression in Chinese Uyghur and Han patients with melanoma.Semantic proximity Read ↗

[BRAF mutation: a novel approach in targeted melanoma therapy].Semantic proximity Read ↗

Targeting KIT in melanoma: a paradigm of molecular medicine and targeted therapeutics.Semantic proximity Read ↗

The clinical significance of KIT mutations in melanoma: a meta-analysis.Semantic proximity Read ↗

Efficacy Evaluation of Imatinib for the Treatment of Melanoma: Evidence From a Retrospective Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.