Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

KIT gene mutations and patterns of protein expression in mucosal and acral melanoma.

Journal of cutaneous medicine and surgery - 1 Jan 2000

Abu-Abed Suzan, Pennell Nancy, Petrella Teresa, Wright Frances, Seth Arun, Hanna Wedad

Abstract excerpt

BACKGROUND: Recently characterized KIT (CD117) gene mutations have revealed new pathways involved in melanoma pathogenesis. In particular, certain subtypes harbor mutations similar to those observed in gastrointestinal stromal tumors, which are sensitive to treatment with tyrosine kinase inhibitors. OBJECTIVE: The purpose of this study was to characterize KIT gene mutations and patterns of protein expression in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Exons
Share to Immunoenzyme Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Melanoma

Share to Mucous Membrane

Share to Neoplasm Grading

Share to Proto-Oncogene Proteins c-kit

Share to Skin Neoplasms

Source

Identifiers

PMID: 22513068
DOI: 10.2310/7750.2011.11064

Genes

KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

KIT gene mutations and patterns of protein expression in mucosal and acral melanoma.PMID 22513068Read ↗

KIT amplification and gene mutations in acral/mucosal melanoma in Korea.Semantic proximity Read ↗

KIT gene mutations and copy number in melanoma subtypes.Semantic proximity Read ↗

Correlation between KIT expression and KIT mutation in melanoma: a study of 173 cases with emphasis on the acral-lentiginous/mucosal type.Semantic proximity Read ↗

Sinonasal, genital and acrolentiginous melanomas show distinct characteristics of KIT expression and mutations.Semantic proximity Read ↗

Large-Scale Analysis of <i>KIT</i> Aberrations in Chinese Patients with MelanomaSemantic proximity Read ↗

Pathological activation of KIT in metastatic tumors of acral and mucosal melanomas.Semantic proximity Read ↗

Analysis of KIT expression and gene mutation in human acral melanoma: with a comparison between primary tumors and corresponding metastases/recurrences.Semantic proximity Read ↗

Acral Melanoma: Review of Clinical, Histologic, and Molecular Findings.Semantic proximity Read ↗

Clinical responses observed with imatinib or sorafenib in melanoma patients expressing mutations in KIT.Semantic proximity Read ↗

KIT and Melanoma: Biological Insights and Clinical Implications.Semantic proximity Read ↗

BRAF, KIT, and NRAS Mutations of Acral Melanoma in White Patients.Semantic proximity Read ↗

Targeting KIT in melanoma: a paradigm of molecular medicine and targeted therapeutics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.