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Article

Associations with smoking and shared epitope differ between IgA- and IgG-class antibodies to cyclic citrullinated peptides in early rheumatoid arthritis.

Arthritis & rheumatology (Hoboken, N.J.) - 1 May 2015

Svärd Anna, Skogh Thomas, Alfredsson Lars, Ilar Anna, Klareskog Lars, Bengtsson Camilla, Kastbom Alf

Abstract excerpt

OBJECTIVE: Smoking and HLA-DRB1/shared epitope (SE) alleles are risk factors for rheumatoid arthritis (RA) characterized by seropositivity for antibodies targeting citrullinated proteins (ACPAs)/cyclic citrullinated peptides (anti-CCP). Previously, mainly IgG-class antibodies have been studied. IgA-class antibodies are to a great extent related to mucosal immunity. The aim of this study was to explore...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25916813
DOI: 10.1002/art.39170

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Associations with smoking and shared epitope differ between IgA- and IgG-class antibodies to cyclic citrullinated peptides in early rheumatoid arthritis.PMID 25916813Read ↗

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