Article
Smoking as a risk factor for rheumatoid arthritis: predominant association with IgA autoantibodies - comprehensive analysis of anti-modified protein antibodies with smoking and genetic risk factors in rheumatoid arthritis.
Arthritis research & therapy - 8 May 2025
van Wesemael Tineke J, Morton Fraser R, Heutz Judith W, Maurits Marc P, Dorjée Annemarie L, Porter Duncan, Huizinga Tom W J, Raza Karim, Toes Rene E M, Knevel Rachel, de Jong Pascal H P, Svärd Anna, van der Woude Diane
Abstract excerpt
BACKGROUND: Rheumatoid arthritis (RA) is an autoimmune disease characterized by the presence of autoantibodies against modified proteins, known as anti-modified protein autoantibodies (AMPAs). While the relationship between different AMPA isotypes and various risk factors remains poorly understood, investigating this association is important for a deeper understanding of RA pathophysiology. Smoking, has its...
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