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Article

Mechanisms of splicing-dependent trans-synaptic adhesion by PTPδ-IL1RAPL1/IL-1RAcP for synaptic differentiation.

Nature communications - 24 Apr 2015

Yamagata Atsushi, Yoshida Tomoyuki, Sato Yusuke, Goto-Ito Sakurako, Uemura Takeshi, Maeda Asami, Shiroshima Tomoko, Iwasawa-Okamoto Shiho, Mori Hisashi, Mishina Masayoshi, Fukai Shuya

Abstract excerpt

Synapse formation is triggered through trans-synaptic interaction between pairs of pre- and postsynaptic adhesion molecules, the specificity of which depends on splice inserts known as 'splice-insert signaling codes'. Receptor protein tyrosine phosphatase δ (PTPδ) can bidirectionally induce pre- and postsynaptic differentiation of neurons by trans-synaptically binding to interleukin-1 receptor accessory protein...

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Identifiers

PMID: 25908590
DOI: 10.1038/ncomms7926
PMCID: PMC4423211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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