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Article

Citosine-Adenine-Repeat Microsatellite of 11β-hydroxysteroid dehydrogenase 2 Gene in Hypertensive Children.

American journal of hypertension - 1 Jan 2016

Valdivia Carolina, Carvajal Cristian A, Campino Carmen, Allende Fidel, Martinez-Aguayo Alejandro, Baudrand Rene, Vecchiola Andrea, Lagos Carlos F, Tapia-Castillo Alejandra, Fuentes Cristobal A, Aglony Marlene, Solari Sandra, Kalergis Alexis M, García Hernan, Owen Gareth I, Fardella Carlos E

Abstract excerpt

BACKGROUND: The impairment of 11β-hydroxysteroid dehydrogenase type 2 enzyme (11βHSD2) results in an inefficient conversion of cortisol to cortisone, which triggers hypertension. Cytosine-adenine repeat (CA repeat) microsatellite has been associated with low HSD11B2 gene expression. AIM: To deter...

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PMID: 25907225
DOI: 10.1093/ajh/hpv052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25907225-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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