Article
NK Cell Development in Times of Innate Lymphoid Cell Diversity.
Frontiers in immunology - 1 Jan 2020
Stokic-Trtica Vladislava, Diefenbach Andreas, Klose Christoph S N
Abstract excerpt
After being described in the 1970s as cytotoxic cells that do not require MHC-dependent pre-activation, natural killer (NK) cells remained the sole member of innate lymphocytes for decades until lymphoid tissue-inducer cells in the 1990s and helper-like innate lymphoid lineages from 2008 onward completed the picture of innate lymphoid cell (ILC) diversity. Since some of the ILC members, such as ILC1s and CCR6-...
Topics
- Animals
- Cell Differentiation
- Cytokines
- Epigenesis, Genetic
- Humans
- Immunity, Innate
- Killer Cells, Natural
- Lymphocyte Activation
- Mice
- MicroRNAs
- Phenotype
- Receptors, Immunologic