Article
Dynamic regulation of innate immune responses in Drosophila by Senju-mediated glycosylation.
Proceedings of the National Academy of Sciences of the United States of America - 5 May 2015
Yamamoto-Hino Miki, Muraoka Masatoshi, Kondo Shu, Ueda Ryu, Okano Hideyuki, Goto Satoshi
Abstract excerpt
The innate immune system is the first line of defense encountered by invading pathogens. Delayed and/or inadequate innate immune responses can result in failure to combat pathogens, whereas excessive and/or inappropriate responses cause runaway inflammation. Therefore, immune responses are tightly regulated from initiation to resolution and are repressed during the steady state. It is well known that glycans...
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