Article
Mutations of γCOP Gene Disturb Drosophila melanogaster Innate Immune Response to Pseudomonas aeruginosa.
International journal of molecular sciences - 10 Jun 2022
Chifiriuc Mariana Carmen, Bologa Alexandru Marian, Ratiu Attila Cristian, Ionascu Adrian, Ecovoiu Alexandru Al
Abstract excerpt
Drosophila melanogaster (the fruit fly) is a valuable experimental platform for modeling host-pathogen interactions. It is also commonly used to define innate immunity pathways and to understand the mechanisms of both host tolerance to commensal microbiota and response to pathogenic agents. Herein, we investigate how the host response to bacterial infection is mirrored in the expression of genes of Imd and Toll...
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