Article
Altered regulation of mesenchymal cell senescence promotes pathological changes associated with diabetic wound healing
2021-06-03
Abstract excerpt
<title>Abstract</title> <p>Pathologic diabetic wound healing is caused by sequential and progressive deterioration of hemostasis, inflammation, proliferation, and resolution/remodeling. Cellular senescence promotes physiological wound process; however, diabetic wounds exhibit low levels of senescent factors and accumulate senescent cells, which impair the healing process. In this study, we demonstrate that the nu...
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Identifiers and source
- Literature Corpus work
- 8817c4e3-d65f-541a-86f2-afab44e8a785
- DOI
- 10.21203/rs.3.rs-568349/v1