Article
IGHV gene usage and mutational status in follicular lymphoma: Correlations with prognosis and patient age.
Leukemia research - 1 Jul 2015
Berget Ellen, Molven Anders, Løkeland Turid, Helgeland Lars, Vintermyr Olav Karsten
Abstract excerpt
Follicular lymphoma (FL) is a heterogeneous disease with some patients developing progressively or transformed disease early, whereas others follow an indolent clinical course. We evaluated the prognostic value of immunoglobulin heavy chain variable (IGHV) gene usage and mutational status in FL patients. One hundred and four IGH sequences were obtained in tumour samples from 99 patients. The IGHV3 subgroup had...
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