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Article

Genetic polymorphisms in the tobacco smoke carcinogens detoxifying enzyme UGT1A7 and the risk of head and neck cancer.

Head & neck - 1 Oct 2009

Lacko Martin, Roelofs Hennie M J, te Morsche Rene H M, Voogd Adri C, Ophuis Michael B Oude, Peters Wilbert H M, Manni Johannes J

Abstract excerpt

BACKGROUND: UGT1A7 is an enzyme involved in the metabolism of (pre)carcinogens present in tobacco smoke. We investigated whether genetic polymorphisms in UGT1A7, with predicted altered enzyme activity, may have a risk-modifying effect on head and neck carcinogenesis. METHODS: Blood samples from 4...

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Identifiers

PMID: 19360737
DOI: 10.1002/hed.21090

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19360737-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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