Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Drosophila pumilio gene encodes two functional protein isoforms that play multiple roles in germline development, gonadogenesis, oogenesis and embryogenesis.

Genetics - 1 Sept 1999

Parisi M, Lin H

Abstract excerpt

The pumilio (pum) gene plays an essential role in embryonic patterning and germline stem cell (GSC) maintenance during oogenesis in Drosophila. Here we report on a phenotypic analysis using pum(ovarette) mutations, which reveals multiple functions of pum in primordial germ cell proliferation, larval ovary formation, GSC division, and subsequent oogenic processes, as well as in oviposition. Specifically, by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Extrachromosomal Inheritance
Share to Germ Cells
Share to Insect Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Weight

Share to Oogenesis

Share to Oviposition

Share to Transgenes

Source

Open in PubMed Open full text

Identifiers

PMID: 10471709
DOI: 10.1093/genetics/153.1.235
PMCID: PMC1460748

Genes

GSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Drosophila pumilio gene encodes two functional protein isoforms that play multiple roles in germline development, gonadogenesis, oogenesis and embryogenesis.PMID 10471709Read ↗

A novel group of pumilio mutations affects the asymmetric division of germline stem cells in the Drosophila ovary.Semantic proximity Read ↗

An Important Role of Pumilio 1 in Regulating the Development of the Mammalian Female Germline1Semantic proximity Read ↗

A gene trap mutation of a murine homolog of the Drosophila stem cell factor Pumilio results in smaller testes but does not affect litter size or fertility.Semantic proximity Read ↗

Maternal Pumilio acts together with Nanos in germline development in Drosophila embryos.Semantic proximity Read ↗

Female-germline specific protein Sakura interacts with Otu and is crucial for germline stem cell renewal and differentiation and oogenesisSemantic proximity Read ↗

Functional analysis of the Drosophila embryonic germ cell transcriptome by RNA interference.Semantic proximity Read ↗

Nanos and Pumilio have critical roles in the development and function of Drosophila germline stem cells.Semantic proximity Read ↗

The ovarian tumor protein isoforms of Drosophila melanogaster exhibit differences in function, expression, and localization.Semantic proximity Read ↗

Identification of new X-chromosomal genes required for Drosophila oogenesis and novel roles for fs(1)Yb, brainiac and dunce.Semantic proximity Read ↗

C. elegans RNA-binding proteins PUF-8 and MEX-3 function redundantly to promote germline stem cell mitosisSemantic proximity Read ↗

Maternal Nanos and Pumilio regulate zygotic vasa expression autonomously in the germ-line progenitors of Drosophila melanogaster embryos.Semantic proximity Read ↗

Redundant control of the Caenorhabditis elegans sperm/oocyte switch by PUF-8 and FBF-1, two distinct PUF RNA-binding proteins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.