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Article

Differential activation of dendritic cells by toll-like receptors causes diverse differentiation of naïve CD4+ T cells from allergic patients.

Allergy - 1 Dec 2014

Deifl S, Kitzmüller C, Steinberger P, Himly M, Jahn-Schmid B, Fischer G F, Zlabinger G J, Bohle B

Abstract excerpt

BACKGROUND: To avert the differentiation of allergen-specific Th2 cells in atopic individuals is a major goal in the prevention and therapy of IgE-mediated allergy. We aimed to compare different toll-like receptor (TLR) agonists regarding their effects on antigen-presenting cells and the differentiation of naïve T cells from allergic patients. METHODS: Monocytes and monocyte-derived dendritic cells (mdDC) from...

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Topics

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Share to Allergens
Share to Antigen-Presenting Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antigens, Surface

Share to CD4-Positive T-Lymphocytes

Share to Dendritic Cells

Share to Hypersensitivity

Share to Immunophenotyping

Share to Toll-Like Receptors

Source

Open in PubMed Open full text

Identifiers

PMID: 25093709
DOI: 10.1111/all.12501
PMCID: PMC4245478

Genes

CCR7
MPL
TLR1
TLR2
TLR4
TLR5
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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