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Article

Population Pharmacokinetic Modeling of Diltiazem in Chinese Renal Transplant Recipients.

European journal of drug metabolism and pharmacokinetics - 1 Feb 2018

Guan Xiao-Feng, Li Dai-Yang, Yin Wen-Jun, Ding Jun-Jie, Zhou Ling-Yun, Wang Jiang-Lin, Ma Rong-Rong, Zuo Xiao-Cong

Abstract excerpt

BACKGROUND AND OBJECTIVES: Diltiazem is a benzothiazepine calcium blocker and widely used in renal transplant patients since it improves the level of tacrolimus or cyclosporine A concentration. Several population pharmacokinetic (PopPK) models had been established for cyclosporine A and tacrolimus but no specific PopPK model was established for diltiazem. The aim of the study is to develop a PopPK model for...

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Source

Identifiers

PMID: 28646274
DOI: 10.1007/s13318-017-0425-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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