Article
Identification of regulatory SNPs associated with genetic modifications in lung adenocarcinoma.
BMC research notes - 24 Mar 2015
Lu Tzu-Pin, Hsiao Chuhsing K, Lai Liang-Chuan, Tsai Mong-Hsun, Hsu Chung-Ping, Lee Jang-Ming, Chuang Eric Y
Abstract excerpt
BACKGROUND: Although much research effort has been devoted to elucidating lung cancer, the molecular mechanism of tumorigenesis still remains unclear. A major challenge to improve the understanding of lung cancer is the difficulty of identifying reproducible differentially expressed genes across independent studies, due to their low consistency. To enhance the reproducibility of the findings, an integrated...
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