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5-methylcytosine RNA methylation regulators affect prognosis and tumor microenvironment in lung adenocarcinoma

1 Mar 2022

Abstract excerpt

Background: Accumulating evidence has shown that 5-methylcytosinec (m5C) RNA methylation plays an essential role in tumorigenesis. However, the roles of m5C regulators in the prognosis, tumor microenvironment (TME), and immunotherapy responses of lung adenocarcinoma (LUAD) have not been fully analyzed. Methods: Based on 14 m5C RNA regulators, we evaluated the m5C RNA modification patterns in patients with LUAD...

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PMID: 35402591
DOI: 10.21037/atm-22-500

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