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Article

CD44 increases the efficiency of distant metastasis of breast cancer.

Oncotarget - 10 May 2015

McFarlane Suzanne, Coulter Jonathan A, Tibbits Paul, O'Grady Anthony, McFarlane Cheryl, Montgomery Nicola, Hill Ashleigh, McCarthy Helen O, Young Leonie S, Kay Elaine W, Isacke Clare M, Waugh David J J

Abstract excerpt

Metastasis is the predominant cause of death from cancer yet we have few biomarkers to predict patients at increased risk of metastasis and are unable to effectively treat disseminated disease. Analysis of 448 primary breast tumors determined that expression of the hylauronan receptor CD44 associated with high grade (p = 0.046), ER- (p = 0.001) and PR-negative tumors (p = 0.029), and correlated with increased...

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Identifiers

PMID: 25888636
DOI: 10.18632/oncotarget.3410
PMCID: PMC4484469

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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