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Article

Cis-regulatory variation is typically polyallelic in Drosophila.

Genetics - 1 Feb 2009

Gruber Jonathan D, Long Anthony D

Abstract excerpt

Gene expression levels vary heritably, with approximately 25-35% of the loci affecting expression acting in cis. We characterized standing cis-regulatory variation among 16 wild-derived strains of Drosophila melanogaster. Our experiment's robust biological and technical replication enabled precise estimates of variation in allelic expression on a high-throughput SNP genotyping platform. We observed concordant,...

Topics

Alleles
Animals
Animals, Wild
Drosophila melanogaster
Female
Gene Expression Regulation
Genes, Insect
Genetic Complementation Test
Genetic Variation
Genetics, Population
Male
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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Open in PubMed Open full text

Identifiers

PMID: 19064705
DOI: 10.1534/genetics.108.098459
PMCID: PMC2644954

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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