Article
Cis-regulatory variation is typically polyallelic in Drosophila.
Genetics - 1 Feb 2009
Gruber Jonathan D, Long Anthony D
Abstract excerpt
Gene expression levels vary heritably, with approximately 25-35% of the loci affecting expression acting in cis. We characterized standing cis-regulatory variation among 16 wild-derived strains of Drosophila melanogaster. Our experiment's robust biological and technical replication enabled precise estimates of variation in allelic expression on a high-throughput SNP genotyping platform. We observed concordant,...
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