Article
Immortalized cell lines from mouse xiphisternum preserve chondrocyte phenotype.
Journal of cellular physiology - 1 Nov 2006
Majumdar Manas K, Chockalingam Priya S, Bhat Ramesh A, Sheldon Richard, Keohan Cristin, Blanchet Tracey, Glasson Sonya, Morris Elisabeth A
Abstract excerpt
Chondrocytes are unique to cartilage and the study of these cells in vitro is important for advancing our understanding of the role of these cells in normal homeostasis and disease including osteoarthritis (OA). As there are limitations to the culture of primary chondrocytes, cell lines have been developed to overcome some of these obstacles. In this study, we developed a procedure to immortalize and characterize...
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