Article
The INCA trial (Impact of NOD2 genotype-guided antibiotic prevention on survival in patients with liver Cirrhosis and Ascites): study protocol for a randomized controlled trial.
Trials - 8 Mar 2015
Casper Markus, Mengel Martin, Fuhrmann Christine, Herrmann Eva, Appenrodt Beate, Schiedermaier Peter, Reichert Matthias, Bruns Tony, Engelmann Cornelius, Grünhage Frank, Lammert Frank
Abstract excerpt
BACKGROUND: Patients with liver cirrhosis have a highly elevated risk of developing bacterial infections that significantly decrease survival rates. One of the most relevant infections is spontaneous bacterial peritonitis (SBP). Recently, NOD2 germline variants were found to be potential predictors of the development of infectious complications and mortality in patients with cirrhosis. The aim of the INCA (Impact...
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