Article
Enhanced production of gamma-aminobutyrate (GABA) in recombinant Corynebacterium glutamicum by expressing glutamate decarboxylase active in expanded pH range.
Microbial cell factories - 15 Feb 2015
Choi Jae Woong, Yim Sung Sun, Lee Seung Hwan, Kang Taek Jin, Park Si Jae, Jeong Ki Jun
Abstract excerpt
BACKGROUND: Gamma-aminobutylate (GABA) is an important chemical in pharmacetucal field and chemical industry. GABA has mostly been produced in lactic acid bacteria by adding L-glutamate to the culture medium since L-glutamate can be converted into GABA by inherent L-glutamate decarboxylase. Recently, GABA has gained much attention for the application as a major building block for the synthesis of 2-pyrrolidone...
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