Article
Co-Localization of GABA Shunt Enzymes for the Efficient Production of Gamma-Aminobutyric Acid via GABA Shunt Pathway in Escherichia coli.
Journal of microbiology and biotechnology - 28 Apr 2016
Pham Van Dung, Somasundaram Sivachandiran, Park Si Jae, Lee Seung Hwan, Hong Soon Ho
Abstract excerpt
Gamma-aminobutyric acid (GABA) is a non-protein amino acid, which is an important inhibitor of neurotransmission in the human brain. GABA is also used as the precursor of biopolymer Nylon-4 production. In this study, the carbon flux from the tricarboxylic acid cycle was directed to the GABA shunt pathway for the production of GABA from glucose. The GABA shunt enzymes succinate-semialdehyde dehydrogenase (GabD)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
