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Article

MET FISH-positive status predicts short progression-free survival and overall survival after gefitinib treatment in lung adenocarcinoma with EGFR mutation.

BMC cancer - 6 Feb 2015

Noro Rintaro, Seike Masahiro, Zou Fenfei, Soeno Chie, Matsuda Kuniko, Sugano Teppei, Nishijima Nobuhiko, Matsumoto Masaru, Kitamura Kazuhiro, Kosaihira Seiji, Minegishi Yuji, Yoshimura Akinobu, Kubota Kaoru, Gemma Akihiko

Abstract excerpt

BACKGROUND: Lung adenocarcinoma patients with EGFR gene mutations have shown a dramatic response to gefitinib. However, drug resistance eventually emerges which limits the mean duration of response. With that in view, we examined the correlations between MET gene status as assessed by fluorescence in situ hybridization (FISH) with overall survival (OS) and progression-free survival (PFS) in adenocarcinoma...

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Identifiers

PMID: 25886066
DOI: 10.1186/s12885-015-1019-1
PMCID: PMC4437672

Genes

MET
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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