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Article

Unraveling the Significance of MET Focal Amplification in Lung Cancer: Integrative NGS, FISH, and IHC Investigation.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Apr 2024

Xiang Chan, Lv Xinze, Chen Ke, Guo Lianying, Zhao Ruiying, Teng Haohua, Ye Min, Kuang Ting, Hou Ting, Liu Chenglin, Du Haiwei, Zhang Zhou, Han Yuchen

Abstract excerpt

MET amplification (METamp) represents a promising therapeutic target in non-small cell lung cancer, but no consensus has been established to identify METamp-dependent tumors that could potentially benefit from MET inhibitors. In this study, an analysis of MET amplification/overexpression status was performed in a retrospectively recruited cohort comprising 231 patients with non-small cell lung cancer from...

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Source

Identifiers

PMID: 38369190
DOI: 10.1016/j.modpat.2024.100451

Genes

MET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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