Article
Clinicopathological characteristics of Non-Small Cell Lung Cancer (NSCLC) patients with c-MET exon 14 skipping mutation, MET overexpression and amplification.
BMC pulmonary medicine - 3 Jul 2023
Ding Caixia, Qiu Yanyi, Zhang Juan, Wei Wei, Gao Hongbian, Yuan Yong, Wang Xiaomin
Abstract excerpt
PURPOSE: MET exon 14 skipping is one of the rare mutations in non-small cell lung cancer (NSCLC), involving its pathogenesis and progression. The performances of several MET inhibitors in clinical trials have been validated based on NGS, immunohistochemistry (IHC), and gene copy number assessments. Thus, a detailed understanding of the relationship between these markers and prognosis is required. METHODS: This...
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