Article
Epidemiology, evolutionary origin, and malaria-induced positive selection effects of G6PD-deficient alleles in Chinese populations.
Molecular genetics & genomic medicine - 1 Dec 2020
Zheng Yuzhong, Wang Junli, Liang Xueyan, Huang Huiying, Ma Yanbo, Lin Liyun, Wang Chunfang, Zhan Xiaofen, Yang Liye, Zha Guangcai, Yang Peikui, Zou Xianghui, Chen Zikai, Chen Xinyao, Chen Weizhong, Liu Xiangzhi, Lin Min
Abstract excerpt
BACKGROUND: Although glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common inherited disorder in the Chinese population, there is scarce evidence regarding the epidemiology, evolutionary origin, and malaria-induced positive selection effects of G6PD-deficient alleles in various Chinese ethnic populations. METHODS: We performed a large population-based screening (n = 15,690) to examine the impact...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.