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Article

Role of SMC1A overexpression as a predictor of poor prognosis in late stage colorectal cancer

3 Mar 2015

Abstract excerpt

BACKGROUND: Structural maintenance of chromosomes 1A (SMC1A) is a member of the cohesion family of proteins that plays crucial roles in cell cycle control. Recent studies have concluded that SMC1A is involved in the pathogenesis of cancer. This study aims to evaluate the functional role of SMC1A in colorectal cancer (CRC) both in vitro and in vivo, and the underlying molecular mechanisms. METHODS: We firstly...

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PMID: 25884313
DOI: 10.1186/s12885-015-1085-4

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