Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel miR-219-SMC4-JAK2/Stat3 regulatory pathway in human hepatocellular carcinoma

30 Jun 2014

Abstract excerpt

BACKGROUND: To understand the involvement of structural maintenance of chromosome 4 (SMC4) in the development and progression of hepatocellular carcinoma (HCC). METHODS: Real-time quantitative PCR and Western Blotting were applied to measure the expression of SMC4 in HCC samples and cell lines. The tumor-promoting effect of SMC4 was determined by WST-1, soft agar colony formation, cell motility and invasion...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Cytokine Signaling Pathways and Interactions
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24980149
DOI: 10.1186/1756-9966-33-55

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel miR-219-SMC4-JAK2/Stat3 regulatory pathway in human hepatocellular carcinomaPMID 24980149Read ↗

Overexpression of the structural maintenance of chromosome 4 protein is associated with tumor de-differentiation, advanced stage and vascular invasion of primary liver cancerSemantic proximity Read ↗

Clinical Significance and Integrative Analysis of the SMC Family in Hepatocellular CarcinomaSemantic proximity Read ↗

Overexpression of SMC4 activates TGFβ/Smad signaling and promotes aggressive phenotype in glioma cellsSemantic proximity Read ↗

Expression Profile and Prognostic Values of SMC Family Members in HCCSemantic proximity Read ↗

SMC4 enhances the chemoresistance of hepatoma cells by promoting autophagySemantic proximity Read ↗

Overexpression of SMC4 predicts a poor prognosis in cervical cancer and facilitates cancer cell malignancy phenotype by activating NF-κB pathway.Semantic proximity Read ↗

SMC4 Promotes Proliferation and Migration of Colon Adenocarcinoma CellsSemantic proximity Read ↗

SMC4, a novel tumor prognostic marker and potential tumor therapeutic targetSemantic proximity Read ↗

Role of SMC1A overexpression as a predictor of poor prognosis in late stage colorectal cancerSemantic proximity Read ↗

MiR-433-3p restrains the proliferation, migration and invasion of glioma cells via targeting SMC4Semantic proximity Read ↗

Non-SMC Condensin I Complex, Subunit G (NCAPG) is a Novel Mitotic Gene Required for Hepatocellular Cancer Cell Proliferation and MigrationSemantic proximity Read ↗

The roles of mutated SWI/SNF complexes in the initiation and development of hepatocellular carcinoma and its regulatory effect on the immune system: A review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.