SMC1A facilitates gastric cancer cells proliferation, migration and invasion via promoting SNAIL activated EMT

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>structural maintenance of chromosomes protein 1A (SMC1A) is a crucial subunit of the cohesion protein complex and plays a vital role in cell cycle regulation, genomic stability maintenance, chromosome dynamics. Recent studies demonstrated that SMC1A participate in tumorigenesis. This reseach aims to explore the role and the underlying mechanisms of SMC1A in gast...

Topics

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• Adenosine Triphosphatases
• Chromosomal Proteins, Non-Histone
• Molecular Targeted Therapy
• Neoplasm Invasiveness
• NF-kappa B
• Nitriles
• Sulfones
• Uterine Cervical Neoplasms

Identifiers and source

Literature Corpus work

1823083c-a417-5b34-995a-833818f3d855

DOI

10.21203/rs.3.rs-2018084/v1