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Article

Overexpression of SMC4 predicts a poor prognosis in cervical cancer and facilitates cancer cell malignancy phenotype by activating NF-κB pathway.

Human cell - 1 Nov 2021

He Hui, Zheng Cui, Tang Yunxian

Abstract excerpt

Cervical cancer is one of the leading female malignancy tumors worldwide. Structural maintenance of chromosomes 4 (SMC4), a member of the SMC family, is associated with cancer pathogenesis and progression. However, the role of SMC4 in cervical cancer is still unclear. In the study, SMC4 was increased in cervical cancer tissues compared with adjacent normal tissues. The SMC4 knockdown and overexpression were...

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PMID: 34480271
DOI: 10.1007/s13577-021-00603-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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