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Article

Common sequence variants associated with coronary artery disease correlate with the extent of coronary atherosclerosis.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2015

Bjornsson Eythor, Gudbjartsson Daniel F, Helgadottir Anna, Gudnason Thorarinn, Gudbjartsson Tomas, Eyjolfsson Kristjan, Patel Riyaz S, Ghasemzadeh Nima, Thorleifsson Gudmar, Quyyumi Arshed A, Thorsteinsdottir Unnur, Thorgeirsson Gudmundur, Stefansson Kari

Abstract excerpt

OBJECTIVE: Single-nucleotide polymorphisms predisposing to coronary artery disease (CAD) have been shown to predict cardiovascular risk in healthy individuals when combined into a genetic risk score (GRS). We examined whether the cumulative burden of known genetic risk variants associated with risk of CAD influences the development and progression of coronary atherosclerosis. APPROACH AND RESULTS: We investigated...

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Identifiers

PMID: 25882067
DOI: 10.1161/ATVBAHA.114.304985
PMCID: PMC5903266

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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