Article
Polymorphisms of the immune response genes: selected biological, methodical and medical aspects.
Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia - 1 Jun 2009
Kubistova Zuzana, Mrazek Frantisek, Petrek Martin
Abstract excerpt
BACKGROUND: Variants of the immune response genes (IRG) are considered a potential source of interindividual differences in both innate and adaptive immune responses. A large number of gene polymorphisms have been reported as alternative forms of the IRG nucleotide sequence with important functional consequences for the structure/expression of immune response molecules. Accordingly, IRG polymorphisms are...
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